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Computational Investigation of Bisphosphate Inhibitors of 3-Deoxy-d-manno-octulosonate 8-phosphate Synthase

The synthase, 3-deoxy-d-manno-octulosonate 8-phosphate (KDO8P), is a key enzyme for the lipopolysaccharide (LPS) biosynthesis of gram-negative bacteria and a potential target for developing new antimicrobial agents. In this study, computational molecular modeling methods were used to determine the c...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Araújo, Jéssica de Oliveira, dos Santos, Alberto Monteiro, Lameira, Jerônimo, Alves, Cláudio Nahum, Lima, Anderson Henrique
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650799/
https://ncbi.nlm.nih.gov/pubmed/31252580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24132370
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