Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation

Immune evasion is a hallmark of cancer and a central mechanism underlying acquired resistance to immune therapy. In allogeneic hematopoietic cell transplantation (alloHCT), late relapses can arise after prolonged alloreactive T-cell control, but the molecular mechanisms of immune escape remain uncle...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Jan, Max, Leventhal, Matthew J., Morgan, Elizabeth A., Wengrod, Jordan C., Nag, Anwesha, Drinan, Samantha D., Wollison, Bruce M., Ducar, Matthew D., Thorner, Aaron R., Leppanen, Scott, Baronas, Jane, Stevens, Jonathan, Lane, William J., Kekre, Natasha, Ho, Vincent T., Koreth, John, Cutler, Corey S., Nikiforow, Sarah, Alyea, Edwin P., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Lindsley, R. Coleman, Ebert, Benjamin L.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650729/
https://ncbi.nlm.nih.gov/pubmed/31324640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000445
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