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A critical role of autophagy in regulating the mesenchymal transition of ductular cells in liver cirrhosis

Our previous studies have shown that autophagy mediates the link between ductular reaction (DR) and liver cirrhosis. Whether the subsequent fibrogenic response is regulated by increased autophagy in DR remains unclear. Here, using both human liver specimens and a rat model of liver cirrhosis induced...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Hung, Tzu-Min, Huang, Yu-Jen, Lin, Yu-Chun, Chen, Yu-Hsuan, Wu, Yao-Ming, Lee, Po-Huang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650611/
https://ncbi.nlm.nih.gov/pubmed/31337842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46764-x
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