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Tyrosine 51 residue of the syndecan-2 extracellular domain is involved in the interaction with and activation of pro-matrix metalloproteinase-7

Although syndecan-2 is known to interact with the matrix metalloproteinase-7 (MMP-7), the details of their interaction were unknown. Our experiments with a series of syndecan-2 extracellular domain deletion mutants show that the interaction is mediated through an interaction of the extracellular dom...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Jang, Bohee, Yun, Ji-Hye, Choi, Sojoong, Park, Jimin, Shin, Dong Hae, Lee, Seung-Taek, Lee, Weontae, Oh, Eok-Soo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650482/
https://ncbi.nlm.nih.gov/pubmed/31337828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47140-5
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