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A Unique Phenylalanine in the Transmembrane Domain Strengthens Homodimerization of the Syndecan-2 Transmembrane Domain and Functionally Regulates Syndecan-2

The syndecans are a type of cell surface adhesion receptor that initiates intracellular signaling events through receptor clustering mediated by their highly conserved transmembrane domains (TMDs). However, the exact function of the syndecan TMD is not yet fully understood. Here, we investigated the...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Kwon, Mi-Jung, Choi, Youngsil, Yun, Ji-Hye, Lee, Weontae, Han, Inn-Oc, Oh, Eok-Soo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2015
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342487/
https://ncbi.nlm.nih.gov/pubmed/25572401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599845
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