The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury

Urine markers can quantify tubular function including reabsorption (α–1 microglobulin (α–1 m)) and β–2 microglobulin (β–2 m)) and protein synthesis (uromodulin). Individuals with tubular dysfunction may be less able to compensate to insults than those without, despite similar estimated glomerular fi...

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Gepubliceerd in:Kidney Int
Hoofdauteurs: Bullen, Alexander L., Katz, Ronit, Lee, Alexandra K., Anderson, Cheryl A.M., Cheung, Alfred K., Garimella, Pranav S., Jotwani, Vasantha, Haley, William E., Ishani, Areef, Lash, James P., Neyra, Javier A., Punzi, Henry, Rastogi, Anjay, Riessen, Erik, Malhotra, Rakesh, Parikh, Chirag R., Rocco, Michael V., Wall, Barry M., Bhatt, Udayan Y., Shlipak, Michael G., Ix, Joachim H., Estrella, Michelle M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650383/
https://ncbi.nlm.nih.gov/pubmed/31262489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.03.024
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