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Urinary biomarkers of tubular damage are associated with mortality but not cardiovascular risk among SPRINT participants with chronic kidney disease

BACKGROUND: Kidney tubulo-interstitial fibrosis on biopsy is a strong predictor of chronic kidney disease (CKD) progression, and CKD is associated with elevated risk of cardiovascular disease (CVD). Tubular health is poorly quantified by traditional kidney function measures, including estimated glom...

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Detalhes bibliográficos
Publicado no:Am J Nephrol
Main Authors: Jotwani, Vasantha K., Lee, Alexandra K., Estrella, Michelle M., Katz, Ronit, Garimella, Pranav S., Malhotra, Rakesh, Rifkin, Dena E., Ambrosius, Walter, Freedman, Barry I., Cheung, Alfred K., Raphael, Kalani L., Drawz, Paul, Neyra, Javier A., Oparil, Suzanne, Punzi, Henry, Shlipak, Michael G., Ix, Joachim H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491265/
https://ncbi.nlm.nih.gov/pubmed/30939472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499531
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