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Urinary biomarkers of tubular damage are associated with mortality but not cardiovascular risk among SPRINT participants with chronic kidney disease

BACKGROUND: Kidney tubulo-interstitial fibrosis on biopsy is a strong predictor of chronic kidney disease (CKD) progression, and CKD is associated with elevated risk of cardiovascular disease (CVD). Tubular health is poorly quantified by traditional kidney function measures, including estimated glom...

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Dettagli Bibliografici
Pubblicato in:Am J Nephrol
Autori principali: Jotwani, Vasantha K., Lee, Alexandra K., Estrella, Michelle M., Katz, Ronit, Garimella, Pranav S., Malhotra, Rakesh, Rifkin, Dena E., Ambrosius, Walter, Freedman, Barry I., Cheung, Alfred K., Raphael, Kalani L., Drawz, Paul, Neyra, Javier A., Oparil, Suzanne, Punzi, Henry, Shlipak, Michael G., Ix, Joachim H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491265/
https://ncbi.nlm.nih.gov/pubmed/30939472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499531
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