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Local nascent protein deposition and remodeling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels

Hydrogels serve as valuable tools for studying cell-extracellular matrix (ECM) interactions in three-dimensional (3D) environments that recapitulate aspects of native ECM. However, the impact of early protein deposition on cell behavior within hydrogels has largely been overlooked. Using a bio-ortho...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Loebel, Claudia, Mauck, Robert L., Burdick, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650309/
https://ncbi.nlm.nih.gov/pubmed/30886401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0307-6
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