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Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

Although cell-matrix adhesive interactions are known to regulate stem cell differentiation, the underlying mechanisms, in particular for direct three-dimensional (3D) encapsulation within hydrogels, are poorly understood. Here, we demonstrate that in covalently crosslinked hyaluronic acid (HA) hydro...

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Hlavní autoři: Khetan, Sudhir, Guvendiren, Murat, Legant, Wesley R., Cohen, Daniel M., Chen, Christopher S., Burdick, Jason A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633615/
https://ncbi.nlm.nih.gov/pubmed/23524375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3586
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