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Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies
Eukaryotic genes are regulated by multivalent transcription factor complexes. Through cooperative self-assembly, these complexes perform non-linear regulatory operations involved in cellular decision-making and signal processing. Here, we apply this design principle to synthetic networks, testing wh...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6650298/ https://ncbi.nlm.nih.gov/pubmed/31000590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau8287 |
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