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Analyses of Mitochondrial DNA and Immune Phenotyping Suggest Accelerated T-cell Turnover in Treated HIV

BACKGROUND: HIV infection is associated with premature aging and mitochondrial integrity is compromised during the aging process. Since mitochondrial toxicity is a consequence of antiretroviral therapies (ART), we hypothesized HIV and long-term ART would correlate with immunosenescence and mitochond...

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Bibliografiske detaljer
Udgivet i:J Acquir Immune Defic Syndr
Main Authors: MASSANELLA, Marta, KARRIS, Maile Y., PÉREZ-SANTIAGO, Josué, YEK, Christina, VITOMIROV, Andrej, MEHTA, Sanjay R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650285/
https://ncbi.nlm.nih.gov/pubmed/30312276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001824
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