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A mitochondrial root to accelerated ageing and frailty

A discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism...

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Detalhes bibliográficos
Publicado no:Nat Rev Endocrinol
Main Authors: Ferrucci, Luigi, Zampino, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462101/
https://ncbi.nlm.nih.gov/pubmed/31992872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41574-020-0319-y
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