Identification of DNA motifs that regulate DNA methylation

DNA methylation is an important epigenetic mark but how its locus-specificity is decided in relation to DNA sequence is not fully understood. Here, we have analyzed 34 diverse whole-genome bisulfite sequencing datasets in human and identified 313 motifs, including 92 and 221 associated with methylat...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Wang, Mengchi, Zhang, Kai, Ngo, Vu, Liu, Chengyu, Fan, Shicai, Whitaker, John W, Chen, Yue, Ai, Rizi, Chen, Zhao, Wang, Jun, Zheng, Lina, Wang, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649826/
https://ncbi.nlm.nih.gov/pubmed/31334813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz483
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