Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite Instability

BACKGROUND: Breast cancers that harbor mismatch-repair (MMR) deficiency and/or microsatellite instability (MSI) might be sensitive to immune checkpoint blockade, but there are currently no specific guidelines for assessing MMR status in breast cancer. Here, we sought to define the clinical value of...

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Publié dans:JNCI Cancer Spectr
Auteurs principaux: Fusco, Nicola, Lopez, Gianluca, Corti, Chiara, Pesenti, Chiara, Colapietro, Patrizia, Ercoli, Giulia, Gaudioso, Gabriella, Faversani, Alice, Gambini, Donatella, Michelotti, Anna, Despini, Luca, Blundo, Concetta, Vaira, Valentina, Miozzo, Monica, Ferrero, Stefano, Bosari, Silvano
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649738/
https://ncbi.nlm.nih.gov/pubmed/31360876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pky056
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