Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite Instability

BACKGROUND: Breast cancers that harbor mismatch-repair (MMR) deficiency and/or microsatellite instability (MSI) might be sensitive to immune checkpoint blockade, but there are currently no specific guidelines for assessing MMR status in breast cancer. Here, we sought to define the clinical value of...

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Detalhes bibliográficos
Publicado no:JNCI Cancer Spectr
Main Authors: Fusco, Nicola, Lopez, Gianluca, Corti, Chiara, Pesenti, Chiara, Colapietro, Patrizia, Ercoli, Giulia, Gaudioso, Gabriella, Faversani, Alice, Gambini, Donatella, Michelotti, Anna, Despini, Luca, Blundo, Concetta, Vaira, Valentina, Miozzo, Monica, Ferrero, Stefano, Bosari, Silvano
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649738/
https://ncbi.nlm.nih.gov/pubmed/31360876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pky056
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