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Solvent viscosity facilitates replication and ribozyme catalysis from an RNA duplex in a model prebiotic process

The RNA World hypothesis posits that RNA was once responsible for genetic information storage and catalysis. However, a prebiotic mechanism has yet to be reported for the replication of duplex RNA that could have operated before the emergence of polymerase ribozymes. Previously, we showed that a vis...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: He, Christine, Lozoya-Colinas, Adriana, Gállego, Isaac, Grover, Martha A, Hud, Nicholas V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649698/
https://ncbi.nlm.nih.gov/pubmed/31170298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz496
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