Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, and Famotidine: A Prospective, Randomized, Crossover Study

BACKGROUND: Concerns about an inhibitory effect of proton pump inhibitors (PPIs) on clopidogrel metabolism have been raised. Because the pharmacological effect of clopidogrel is dependent on genetically determined activity of the hepatic cytochrome P450 isoenzymes system, it is important to examine...

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Vydáno v:Clin Cardiol
Hlavní autoři: Arbel, Yaron, Birati, Edo Y., Finkelstein, Ariel, Halkin, Amir, Kletzel, Hanna, Abramowitz, Yigal, Berliner, Shlomo, Deutsch, Varda, Herz, Itzhak, Keren, Gad, Banai, Shmuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Periodicals, Inc. 2013
Témata:
Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649548/
https://ncbi.nlm.nih.gov/pubmed/23630016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22117
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