Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, and Famotidine: A Prospective, Randomized, Crossover Study

BACKGROUND: Concerns about an inhibitory effect of proton pump inhibitors (PPIs) on clopidogrel metabolism have been raised. Because the pharmacological effect of clopidogrel is dependent on genetically determined activity of the hepatic cytochrome P450 isoenzymes system, it is important to examine...

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Bibliografiska uppgifter
I publikationen:Clin Cardiol
Huvudupphovsmän: Arbel, Yaron, Birati, Edo Y., Finkelstein, Ariel, Halkin, Amir, Kletzel, Hanna, Abramowitz, Yigal, Berliner, Shlomo, Deutsch, Varda, Herz, Itzhak, Keren, Gad, Banai, Shmuel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley Periodicals, Inc. 2013
Ämnen:
Clinical Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649548/
https://ncbi.nlm.nih.gov/pubmed/23630016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.22117
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