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Functional polymorphism of thymidylate synthase, but not of the COMT and IL‐1B genes, is associated with breast cancer

Polymorphic variations may affect the rate of gene transcription, the stability of the mRNA, or the quantity and activity of the resulting protein. In this study we evaluated the association between the interleukin‐1B C‐31T, catechol‐O‐methyltransferase Val158Met, and thymidylate synthase (TS) 1494d...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Akisik, Elif, Dalay, Nejat
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649245/
https://ncbi.nlm.nih.gov/pubmed/17385677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.20139
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