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Simultaneous Prediction of Cosolvent Influence on Reaction Equilibrium and Michaelis Constants of Enzyme-Catalyzed Ketone Reductions

[Image: see text] Understanding and quantification of cosolvent influences on enzyme-catalyzed reactions are driven by a twofold interest. On the one hand, cosolvents can simulate the cellular environment for deeper understanding of in cellulo reaction conditions. On the other hand, cosolvents are a...

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Publicat a:ACS Omega
Autors principals: Wangler, Anton, Hüser, Aline, Sadowski, Gabriele, Held, Christoph
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648939/
https://ncbi.nlm.nih.gov/pubmed/31459767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03159
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