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Potent CYP3A4 Inhibitors Derived from Dillapiol and Sesamol

[Image: see text] Synthesis of 50 analogues of the natural insecticide synergists, dillapiol and sesamol, is reported. These were evaluated as potential insecticide synergists based on their inhibition of human CYP3A4. The most potent inhibitors have a relatively large hydrophobic substituent at eit...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Francis Carballo-Arce, Ana, Raina, Vikrant, Liu, Suqi, Liu, Rui, Jackiewicz, Victoria, Carranza, David, Arnason, John Thor, Durst, Tony
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648837/
https://ncbi.nlm.nih.gov/pubmed/31460189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00897
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