Amish (Rural) vs. non-Amish (Urban) Infant Fecal Microbiotas Are Highly Diverse and Their Transplantation Lead to Differences in Mucosal Immune Maturation in a Humanized Germfree Piglet Model

The gut microbiome plays an important role in the immune system development, maintenance of normal health status, and in disease progression. In this study, we comparatively examined the fecal microbiomes of Amish (rural) and non-Amish (urban) infants and investigated how they could affect the mucos...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Dhakal, Santosh, Wang, Lingling, Antony, Linto, Rank, Jennifer, Bernardo, Pauline, Ghimire, Shristi, Bondra, Kathy, Siems, Christina, Lakshmanappa, Yashavanth Shaan, Renu, Sankar, Hogshead, Bradley, Krakowka, Steven, Kauffman, Mike, Scaria, Joy, LeJeune, Jeffrey T., Yu, Zhongtang, Renukaradhya, Gourapura J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648804/
https://ncbi.nlm.nih.gov/pubmed/31379808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01509
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