A Nanoparticle-Poly(I:C) Combination Adjuvant Enhances the Breadth of the Immune Response to Inactivated Influenza Virus Vaccine in Pigs

Intranasal vaccination elicits secretory IgA (SIgA) antibodies in the airways, which is required for cross-protection against influenza. To enhance the breadth of immunity induced by a killed swine influenza virus antigen (KAg) or conserved T cell and B cell peptides, we adsorbed the antigens togeth...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Renu, Sankar, Feliciano-Ruiz, Ninoshkaly, Lu, Fangjia, Ghimire, Shristi, Han, Yi, Schrock, Jennifer, Dhakal, Santosh, Patil, Veerupaxagouda, Krakowka, Steven, HogenEsch, Harm, Renukaradhya, Gourapura J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349929/
https://ncbi.nlm.nih.gov/pubmed/32443416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8020229
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