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Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

This article describes pathogenic concepts and factors, in particular glycolipid abnormalities, that create cell dysfunction and synaptic loss in neurodegenerative diseases. By phenocopying lysosomal storage disorders, such as Gaucher disease and related disorders, age- and dose-dependent changes in...

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Pubblicato in:J Neuroinflammation
Autori principali: Hallett, Penelope J., Engelender, Simone, Isacson, Ole
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647317/
https://ncbi.nlm.nih.gov/pubmed/31331333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1532-2
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