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Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

This article describes pathogenic concepts and factors, in particular glycolipid abnormalities, that create cell dysfunction and synaptic loss in neurodegenerative diseases. By phenocopying lysosomal storage disorders, such as Gaucher disease and related disorders, age- and dose-dependent changes in...

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Foilsithe in:J Neuroinflammation
Main Authors: Hallett, Penelope J., Engelender, Simone, Isacson, Ole
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647317/
https://ncbi.nlm.nih.gov/pubmed/31331333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1532-2
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