Cholesterol efflux alterations in adolescent obesity: role of adipose-derived extracellular vesical microRNAs

BACKGROUND: Macrophage cholesterol efflux capacity has been identified as a predictor for cardiovascular disease. We assessed the relationship between adipocyte-derived extracellular vesicle microRNAs and macrophage cholesterol efflux capacity. METHODS: We assessed an adolescent cohort (n = 93, Age,...

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Pubblicato in:J Transl Med
Autori principali: Barberio, Matthew D., Kasselman, Lora J., Playford, Martin P., Epstein, Samuel B., Renna, Heather A., Goldberg, Madeleine, DeLeon, Joshua, Voloshyna, Iryna, Barlev, Ashley, Salama, Michael, Ferrante, Sarah C., Nadler, Evan P., Mehta, Nehal, Reiss, Allison B., Freishtat, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647309/
https://ncbi.nlm.nih.gov/pubmed/31331347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1980-6
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