Infliximab Reverses Suppression of Cholesterol Efflux Proteins by TNF-α: A Possible Mechanism for Modulation of Atherogenesis

Tumor necrosis factor- (TNF-) α is a proinflammatory proatherogenic cytokine. Infliximab, an anti-TNF-α monoclonal antibody, is effective in treating rheumatoid arthritis. However, its impact on cardiovascular burden and lipid transport is unclear. The present study investigates the effect of TNF-α...

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Autors principals: Voloshyna, Iryna, Seshadri, Sangeetha, Anwar, Kamran, Littlefield, Michael J., Belilos, Elise, Carsons, Steven E., Reiss, Allison B.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920897/
https://ncbi.nlm.nih.gov/pubmed/24587984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/312647
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