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CRISPR/Cas9 Mutagenesis and Expression of Dominant Mutant Transgenes as Functional Genomic Approaches in Parasitic Nematodes

DNA transformation of parasitic nematodes enables novel approaches to validating predictions from genomic and transcriptomic studies of these important pathogens. Notably, proof of principle for CRISPR/Cas9 mutagenesis has been achieved in Strongyloides spp., allowing identification of molecules ess...

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Bibliografiska uppgifter
I publikationen:Front Genet
Huvudupphovsman: Lok, James B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646703/
https://ncbi.nlm.nih.gov/pubmed/31379923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00656
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