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Neuronal Circuit-Based Computer Modeling as a Phenotypic Strategy for CNS R&D
With the success rate of drugs for CNS indications at an all-time low, new approaches are needed to turn the tide of failed clinical trials. This paper reviews the history of CNS drug Discovery over the last 60 years and proposes a new paradigm based on the lessons learned. The initial wave of succe...
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| Publicat a: | Front Neurosci |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6646593/ https://ncbi.nlm.nih.gov/pubmed/31379482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00723 |
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