USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells

Tau aggregates in neurons of brain lesions is a hallmark pathology of tauopathies, including Alzheimer’s disease (AD). Recent studies suggest that the RNA-binding protein TIA1 initiates Tau aggregation by inducing the formation of stress granules (SGs) containing Tau. SGs are stress-inducible cytopl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Piatnitskaia, Svetlana, Takahashi, Masahiko, Kitaura, Hiroki, Katsuragi, Yoshinori, Kakihana, Taichi, Zhang, Lu, Kakita, Akiyoshi, Iwakura, Yuriko, Nawa, Hiroyuki, Miura, Takeshi, Ikeuchi, Takeshi, Hara, Toshifumi, Fujii, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646309/
https://ncbi.nlm.nih.gov/pubmed/31332267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47033-7
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