Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells

Natriuretic peptide type C (NPPC) secreted by mural granulosa cells (MGCs) maintains oocyte meiotic arrest via the activation of guanylyl cyclase-linked natriuretic peptide receptor 2 (NPR2). Here, we investigated the effect of transforming growth factor (TGF)-β on NPPC expression in MGCs and oocyte...

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Publicat a:Cell Death Dis
Autors principals: Yang, Jing, Zhang, Yu, Xu, Xiaoting, Li, Jia, Yuan, Feifei, Bo, Shumin, Qiao, Jie, Xia, Guoliang, Su, Youqiang, Zhang, Meijia
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646305/
https://ncbi.nlm.nih.gov/pubmed/31332164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1797-5
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