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Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes

Granulosa cells of mammalian Graafian follicles maintain oocytes in meiotic arrest, which prevents the precocious maturation. We show that mouse mural granulosa cells, which line the follicle wall, express natriuretic peptide precursor type C, Nppc, mRNA while cumulus cells surrounding oocytes expre...

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Bibliografiske detaljer
Main Authors: Zhang, Meijia, Su, You-Qiang, Sugiura, Koji, Xia, Guoliang, Eppig, John J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056542/
https://ncbi.nlm.nih.gov/pubmed/20947764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1193573
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