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Contrasting Effects of Guanidinium Chloride and Urea on the Activity and Unfolding of Lysozyme

[Image: see text] Cosolvents play an important role in regulating the stability and function of proteins present in the cell. We studied the role of cosolvents, urea and guanidinium chloride (GdmCl), which act as protein denaturants, in the catalytic activity and structural stability of the protein...

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Publicat a:ACS Omega
Autors principals: Biswas, Biswajit, Muttathukattil, Aswathy N., Reddy, Govardhan, Singh, Prashant Chandra
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644995/
https://ncbi.nlm.nih.gov/pubmed/31458105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01911
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