Chemical Ligand Space of Cereblon

[Image: see text] The protein cereblon serves as a substrate receptor of a ubiquitin ligase complex that can be tuned toward different target proteins by cereblon-binding agents. This approach to targeted protein degradation is exploited in different clinical settings and has sparked the development...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Omega
Egile Nagusiak: Boichenko, Iuliia, Bär, Kerstin, Deiss, Silvia, Heim, Christopher, Albrecht, Reinhard, Lupas, Andrei N., Hernandez Alvarez, Birte, Hartmann, Marcus D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2018
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644994/
https://ncbi.nlm.nih.gov/pubmed/31459225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00959
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