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Total Synthesis of (±)-Allocolchicine and Its Analogues Using Co-Catalyzed Alkyne [2 + 2 + 2]-Cyclotrimerization

[Image: see text] The total synthesis of (±)-allocolchicine has been completed by employing cobalt-catalyzed alkyne [2 + 2 + 2]-cyclotrimerization as the key reaction. The essential diyne has been synthesized from easily available 3,4,5-trimethoxybenzaldehyde following simple chemical transformation...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Paymode, Dinesh J., Ramana, Chepuri V.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644368/
https://ncbi.nlm.nih.gov/pubmed/31457824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00980
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