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Metal-Catalyzed Cyclotrimerization Reactions of Cyanamides: Synthesis of 2-Aryl-α-carbolines

The synthesis of annulated 2-aryl-α-carboline heterocycles is described using transition metal catalysis. A linear strategy is described that uses Rh(I) catalysis to form the α-carboline scaffold by [2+2+2] cyclotrimerization. Alternatively, a tandem catalytic approach using a Pd(II) precatalyst aff...

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Vydáno v:Org Lett
Hlavní autoři: Medas, Kyle M., Lesch, Robert W., Edioma, Friendship B., Wrenn, Sean P., Ndahayo, Vincent, Mulcahy, Seann P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895322/
https://ncbi.nlm.nih.gov/pubmed/32255636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c00891
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