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Targeted knock-in mice with a human mutation in GRTH/DDX25 reveals the essential role of phosphorylated GRTH in spermatid development during spermatogenesis

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) is a testis specific member of the DEAD-box family of RNA helicases expressed in meiotic and haploid germ cells which plays an essential role in spermatogenesis. There are two species of GRTH the 56 kDa non-phospho and 61 kDa phospho forms....

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Detalles Bibliográficos
Publicado en:Hum Mol Genet
Main Authors: Kavarthapu, Raghuveer, Anbazhagan, Rajakumar, Raju, Murugananthkumar, Morris, Chon-Hwa Tsai, Pickel, James, Dufau, Maria L
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644162/
https://ncbi.nlm.nih.gov/pubmed/31009948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz079
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