Calcimimetic R568 improved cardiac remodeling by classic and novel renin-angiotensin system in spontaneously hypertensive rats

One major cause of cardiac mortality is heart disease caused by hypertension. The formation of cyclic adenosine monophosphate (cAMP) is inhibited by calcium-sensitive receptor (CaSR) activation which increases intracellular Ca(2+) concentrations and suppresses renin release. As we know, renin-angiot...

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Detalles Bibliográficos
Publicado en:Exp Biol Med (Maywood)
Main Authors: Zhang, Tian, Tang, Na, Xi, Dongmei, Zhao, Yongli, Liu, Yongmin, Wang, Lamei, Tang, Yan, Zhang, Xiaoni, Zhong, Hua, He, Fang
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2019
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643192/
https://ncbi.nlm.nih.gov/pubmed/31159562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219854325
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