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Calcimimetic R568 reduced the blood pressure and improved aortic remodeling in spontaneously hypertensive rats by inhibiting local renin-angiotensin system activity
Hypertension is a cardiovascular disease that seriously affects human health. Activation of the calcium-sensing receptor (CaSR) inhibits cyclic adenosine monophosphate (cAMP) formation by increasing [Ca(2+)](i) and subsequently inhibiting renin release. The renin-angiotensin system (RAS) plays an im...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200994/ https://ncbi.nlm.nih.gov/pubmed/30402152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6734 |
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