Mature osteoclast–derived apoptotic bodies promote osteogenic differentiation via RANKL-mediated reverse signaling

In bone remodeling, after a lifespan of ∼2 weeks, osteoclasts undergo apoptosis in each bone turnover cycle, resulting in generation of a large number of apoptotic bodies (ABs). However, the biological roles of osteoclast-derived ABs (OC-ABs) in bone remodeling have not been investigated and remain...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ma, Qinyu, Liang, Mengmeng, Wu, Yutong, Ding, Ning, Duan, Lianli, Yu, Tao, Bai, Yun, Kang, Fei, Dong, Shiwu, Xu, Jianzhong, Dou, Ce
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643026/
https://ncbi.nlm.nih.gov/pubmed/31167789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007625
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