IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis

A variety of osteolytic factors have been identified from breast cancer cells leading to osteolysis, but less is known about which factor plays an essential role in the initiation process prior to the overt vicious osteolytic cycle. Here, we present in vitro and in vivo evidences to clarify the role...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Liang, Mengmeng, Ma, Qinyu, Ding, Ning, Luo, Fei, Bai, Yun, Kang, Fei, Gong, Xiaoshan, Dong, Rui, Dai, Jingjin, Dai, Qijie, Dou, Ce, Dong, Shiwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491651/
https://ncbi.nlm.nih.gov/pubmed/31040267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1594-1
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