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GluN2A-NMDA receptor–mediated sustained Ca(2+) influx leads to homocysteine-induced neuronal cell death
Homocysteine, a metabolite of the methionine cycle, is a known agonist of N-methyl-d-aspartate receptor (NMDAR), a glutamate receptor subtype and is involved in NMDAR-mediated neurotoxicity. Our previous findings have shown that homocysteine-induced, NMDAR-mediated neurotoxicity is facilitated by a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643025/ https://ncbi.nlm.nih.gov/pubmed/31167782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008820 |
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