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One protein to rule them all: the role of CCCTC-binding factor in shaping Human genome in health and disease

The eukaryotic genome, constituting several billion base pairs, must be contracted to fit within the volume of a nucleus where the diameter is on the scale of µm. The 3D structure and packing of such a long sequence, cannot be left to pure chance, as DNA must be efficiently used for its primary role...

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Publicat a:Semin Cell Dev Biol
Autors principals: Lazniewski, Michal, Dawson, Wayne K., Rusek, Anna Maria, Plewczynski, Dariusz
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642822/
https://ncbi.nlm.nih.gov/pubmed/30096365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2018.08.003
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