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One protein to rule them all: the role of CCCTC-binding factor in shaping Human genome in health and disease
The eukaryotic genome, constituting several billion base pairs, must be contracted to fit within the volume of a nucleus where the diameter is on the scale of µm. The 3D structure and packing of such a long sequence, cannot be left to pure chance, as DNA must be efficiently used for its primary role...
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| Publicado no: | Semin Cell Dev Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642822/ https://ncbi.nlm.nih.gov/pubmed/30096365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2018.08.003 |
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