AKAP6 and phospholamban colocalize and interact in HEK‐293T cells and primary murine cardiomyocytes

Phospholamban (PLN) is an important Ca(2+) modulator at the sarcoplasmic reticulum (SR) of striated muscles. It physically interacts and inhibits sarcoplasmic reticulum Ca(2+) ATPase (SERCA2) function, whereas a protein kinase A (PKA)‐dependent phosphorylation at its serine 16 reverses the inhibitio...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Hakem Zadeh, Farigol, Teng, Allen C. T., Kuzmanov, Uros, Chambers, Paige J., Tupling, Allan R., Gramolini, Anthony O.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642276/
https://ncbi.nlm.nih.gov/pubmed/31325238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14144
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