Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow

Innate lymphoid cells (ILCs) play strategic roles in tissue homeostasis and immunity. ILCs arise from lymphoid progenitors undergoing lineage restriction and the development of specialized ILC subsets. We generated “5x polychromILC” transcription factor reporter mice to delineate ILC precursor state...

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Gepubliceerd in:Immunity
Hoofdauteurs: Walker, Jennifer A., Clark, Paula A., Crisp, Alastair, Barlow, Jillian L., Szeto, Aydan, Ferreira, Ana C.F., Rana, Batika M.J., Jolin, Helen E., Rodriguez-Rodriguez, Noe, Sivasubramaniam, Meera, Pannell, Richard, Cruickshank, James, Daly, Maria, Haim-Vilmovsky, Liora, Teichmann, Sarah A., McKenzie, Andrew N.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642165/
https://ncbi.nlm.nih.gov/pubmed/31128961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.05.002
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