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Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy

Perinatally-acquired HIV has persistent effects on long-term health outcomes, even after early treatment. We hypothesize that epigenetic indicators, such as DNA methylation, may elucidate cellular processes that explain these effects. Here, we compared DNA methylation profiles in whole blood from 12...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shiau, Stephanie, Strehlau, Renate, Wang, Shuang, Violari, Avy, Do, Catherine, Patel, Faeezah, Liberty, Afaaf, Krupska, Izabela, Arpadi, Stephen M., Foca, Marc, Coovadia, Ashraf, Abrams, Elaine J., Tycko, Benjamin, Terry, Mary Beth, Kuhn, Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642153/
https://ncbi.nlm.nih.gov/pubmed/31324826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46930-1
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