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Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells

Although the biological systems in the human body are affected by the earth’s gravity, information about the underlying molecular mechanisms is limited. For example, apoptotic signaling is enhanced in cancer cells subjected to microgravity. We reasoned that signaling regulated by p53 may be involved...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fukazawa, Takahiro, Tanimoto, Keiji, Shrestha, Looniva, Imura, Takeshi, Takahashi, Shinya, Sueda, Taijiro, Hirohashi, Nobuyuki, Hiyama, Eiso, Yuge, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641656/
https://ncbi.nlm.nih.gov/pubmed/31323026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219363
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