Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions

Tumor hypoxia contributes to a biologically aggressive phenotype and therapeutic resistance. Recent studies have revealed that hypoxia reduces expression of several DNA damage recognition and repair (DRR) genes via both hypoxia-inducible factor (HIF)-independent and -dependent pathways, and this ind...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakamura, Hideaki, Bono, Hidemasa, Hiyama, Keiko, Kawamoto, Takeshi, Kato, Yukio, Nakanishi, Takeshi, Nishiyama, Masahiko, Hiyama, Eiso, Hirohashi, Nobuyuki, Sueoka, Eisaburo, Poellinger, Lorenz, Tanimoto, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821451/
https://ncbi.nlm.nih.gov/pubmed/29466367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192136
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