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Direct/Reversible Amidation of Troponyl Alkylglycinates via Cationic Troponyl Lactones and Mechanistic Insights

[Image: see text] The conversion of troponyl alkylglycinate acid/ester/amide derivatives (Trag acid/ester/amide) into cationic troponyl lactones (CTLs) in the presence of trifluoroacetic acid and their amidation with amines is described. The reversible amidation of Trag amides, that is, the cleavage...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Balachandra, Chenikkayala, Sharma, Nagendra K.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2018
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641332/
https://ncbi.nlm.nih.gov/pubmed/31457944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01540
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