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Structure of Spherulites in Insulin, β-Lactoglobulin, and Amyloid β

[Image: see text] Under denaturing conditions such as low pH and elevated temperatures, proteins in vitro can misfold and aggregate to form long rigid rods called amyloid fibrils; further self-assembly can lead to larger structures termed spherulites. Both of these aggregates resemble amyloid tangle...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Omega
Main Authors: Cannon, Danielle, Eichhorn, Stephen J., Donald, Athene M.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2016
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640738/
https://ncbi.nlm.nih.gov/pubmed/31457172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00208
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